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Allogeneic mesoangioblasts give rise to alpha-sarcoglycan expressing fibers when transplanted into dystrophic mice.

Description : Cell therapy for muscular dystrophy involves transplantation of either genetically modified autologous cells or normal donor cells that will be rejected unless the host is adequately immune suppressed. The extent of the immune response appears to be mitigated in this case of stem cells, by immune-su...
Language(s) : English
Subject(s) : Animals, Blood Vessels, CD4-Positive T-Lymphocytes, Gene Expression, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Muscle Fibers, Skeletal, Muscular Dystrophy, Animal, Mutation, Sarcoglycans, Stem Cell Transplantation, Transplantation, Homologous
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Publication Date(s) : 2006-11-15